美國(guó)PrimCells原代細(xì)胞：PrimCells的原代細(xì)胞產(chǎn)品采用獨(dú)特的高效提取方法， 分離，并通過(guò)盡量縮短體外培養(yǎng)時(shí)間從而保證其更接近體原始狀態(tài)，以適應(yīng)客戶(hù)對(duì)細(xì)胞品質(zhì)的嚴(yán)格要求。PrimCells亦是多種腎臟來(lái)源原代細(xì)胞的世界**供應(yīng)商，為多家知名**研發(fā)企業(yè)提供**藥效與毒理測(cè)試。此外，PrimCells還開(kāi)發(fā)出多種轉(zhuǎn)基因胚胎干細(xì)胞、原代胚胎成纖維細(xì)胞等產(chǎn)品，是干細(xì)胞與重編程領(lǐng)域**的報(bào)告基因原代細(xì)胞提供商。
| Species: | Sprague Dawley | Catalog Number: | PCKDR01 |
| Cell Number: | ~1x106 | Storage/Shipping: | Freshly Isolated |
Introduction:
Podocytes are a group of terminally differentiated cells located in the outer aspect of glomerular basement membrane (GBM). They have special morphology with multiple long foot processes that cover the entire outer surface of the capillary of glomerulus and form a tight barrier to filter the blood and form the initial urine1. These cells are very important to maintain the normal function of the kidney and podocyte injury could result in massive proteinuria and eventually kidney failure2, 3.
PrimCells is proud to isolate and provide the primary cultures of podocytes from Sprague Dawley rats to the research community. These cells have been isolated using traditional sieving method and are confirmed to express typical podocyte markers such as Nephrin, Synaptopodin and WT1 and can be a valuable tool to study the function of genes in nephrology and/or drug induced toxicity in glomerular injury.
PrimCells是位于美國(guó)加州圣迭戈的一家專(zhuān)業(yè)致力于細(xì)胞產(chǎn)品研發(fā)和解決方案提供的業(yè)內(nèi)技術(shù)領(lǐng)導(dǎo)企業(yè)。
公司匯集了**的生物醫(yī)藥技術(shù)專(zhuān)家，獨(dú)立開(kāi)發(fā)了多項(xiàng)原代細(xì)胞和干細(xì)胞相關(guān)的專(zhuān)有技術(shù)。 公司以“細(xì)胞研究的選擇”為宗旨，自主研發(fā)超過(guò)70種**產(chǎn)品，填補(bǔ)了多個(gè)特種細(xì)胞市場(chǎng)的空白。例如其誘導(dǎo)性表達(dá)細(xì)胞庫(kù)和高效3D皮膚培養(yǎng)系統(tǒng)，皆為該類(lèi)產(chǎn)品目前市場(chǎng)上少數(shù)的規(guī)模化供應(yīng)商。此外，公司以高質(zhì)量的數(shù)據(jù)與快速穩(wěn)定的項(xiàng)目完成時(shí)間，長(zhǎng)期為多家知名制藥公司提供解決方案，獲得用戶(hù)廣泛贊譽(yù)。
PrimCells產(chǎn)品線：
PrimCells 解決方案
1.誘導(dǎo)性穩(wěn)定細(xì)胞株開(kāi)發(fā) 2. 原代細(xì)胞開(kāi)發(fā) 3. **體外毒理和效能測(cè)試 4. 3D-皮膚培養(yǎng)
PrimCells合作伙伴及客戶(hù):
A．生物制藥公司：輝瑞(Pfizer), 諾華(Novartis), 禮來(lái)(Eli2 Lilly),. Amgen, EMD Millipore, Regeneron等公司的毒理和醫(yī)藥研發(fā)部門(mén)
B．科研機(jī)構(gòu)：冷泉港實(shí)驗(yàn)室，哈佛醫(yī)學(xué)院, 麻省理工（MIT）,， UCSF, NYU, Salk, UIUC, USC等
