美國(guó)Cas9可誘導(dǎo)表達(dá)C2C12穩(wěn)定細(xì)胞株（CRISPR適用）
美國(guó)PrimCells誘導(dǎo)性穩(wěn)定細(xì)胞株： PrimCells建立的獨(dú)有的誘導(dǎo)性細(xì)胞高效開(kāi)發(fā)系統(tǒng)，能在極短時(shí)間內(nèi)篩選出低泄漏，高誘導(dǎo)性的穩(wěn)定細(xì)胞株，成功開(kāi)發(fā)出一系列核受體誘導(dǎo)表達(dá)的穩(wěn)定細(xì)胞株產(chǎn)品，為多家知名制藥公司研發(fā)部門(mén)和科研院所提供產(chǎn)品與服務(wù)，廣受用戶好評(píng)。針對(duì)客戶的特定需求，PrimCells亦提供量身定制服務(wù)，通過(guò)密切的客戶交流和高效的篩選體系，嚴(yán)格保證客戶在3-4周內(nèi)即獲得高質(zhì)量的誘導(dǎo)性穩(wěn)定細(xì)胞株，具有市場(chǎng)其他供應(yīng)商無(wú)可比擬的時(shí)效性。
Introduction

CRISPR, the Clustered Regularly Interspaced Short Palindromic Repeats, is currently the most commonly used technology for genome editing. There are two distinct components in this system: a guide RNA and an RNA-guided DNA nuclease, Cas9 (CRISPR associated protein 9). When these two components are expressed together in the same cells, the genomic sequence targeted by the gRNA will be edited (modified or permanently disrupted).
Given the immediate availability of mouse and human lentiviral CRISPR gRNA libraries, CRISPR technology has tremendously benefitted the scientific community in both academia and industry. PrimCells now is providing tetracycline inducible Cas9 expressing cell lines of a variety of tissue origin to further facilitate high-throughput, CRISPR based genome-wide screening. This cell line is puromycin resistant and tetracycline inducible.

美國(guó)PrimCells品牌介紹
PrimCells是位于美國(guó)加州圣迭戈的一家專業(yè)致力于細(xì)胞產(chǎn)品研發(fā)和解決方案提供的業(yè)內(nèi)技術(shù)領(lǐng)導(dǎo)企業(yè)。
公司匯集了**的生物醫(yī)藥技術(shù)專家，獨(dú)立開(kāi)發(fā)了多項(xiàng)原代細(xì)胞和干細(xì)胞相關(guān)的專有技術(shù)。 公司以“細(xì)胞研究的選擇”為宗旨，自主研發(fā)超過(guò)70種**產(chǎn)品，填補(bǔ)了多個(gè)特種細(xì)胞市場(chǎng)的空白。例如其誘導(dǎo)性表達(dá)細(xì)胞庫(kù)和高效3D皮膚培養(yǎng)系統(tǒng)，皆為該類產(chǎn)品目前市場(chǎng)上少數(shù)的規(guī)模化供應(yīng)商。此外，公司以高質(zhì)量的數(shù)據(jù)與快速穩(wěn)定的項(xiàng)目完成時(shí)間，長(zhǎng)期為多家知名制藥公司提供解決方案，獲得用戶廣泛贊譽(yù)。   
PrimCells產(chǎn)品線：

• 報(bào)告基因干細(xì)胞        2. 原代細(xì)胞（含報(bào)告基因原代細(xì)胞）               3. 誘導(dǎo)性穩(wěn)定細(xì)胞株

4. 人源重組蛋白               5.   **型培養(yǎng)試劑      
PrimCells 解決方案
1.誘導(dǎo)性穩(wěn)定細(xì)胞株開(kāi)發(fā) 2. 原代細(xì)胞開(kāi)發(fā) 3. **體外毒理和效能測(cè)試 4. 3D-皮膚培養(yǎng)
PrimCells合作伙伴及客戶:
A．生物制藥公司：輝瑞(Pfizer), 諾華(Novartis), 禮來(lái)(Eli2  Lilly),. Amgen, EMD Millipore, Regeneron等公司的毒理和醫(yī)藥研發(fā)部門(mén)
B．科研機(jī)構(gòu)：冷泉港實(shí)驗(yàn)室，哈佛醫(yī)學(xué)院, 麻省理工（MIT）,， UCSF, NYU, Salk, UIUC, USC等